Raaf schreef: ↑wo 22 jan 2020, 08:41
@Lizzy als ik vragen mag:
Nou ben ik wel benieuwd geworden naar de nadelen van (een lage dosis) THC voor honden, omdat ik wel de voordelen ken...
Doel je dan op leverenzyminductie of ook nog op andere punten?
Ik weet er niet zoveel van maar ene Dr. Robert Silver heeft zich gespecialiseerd in CBD en CBD + THC olie bij honden en hij schreef dit:
Medical Marijuana Safe to Give to My Pet?
Studies conducted in the 1970’s found that dogs have the highest number of THC receptors in their brains, more than any other animal studied, including humans. A lot of these receptors are located in the area of the brain that governs coordination. A dog who gets too much THC will have an initial and brief period of excitement, then act very disoriented, may drool, may urinate on itself and will stand in one place rocking back and forth unable to move forward. They may fall over onto their side. We call this neurologic reaction: “Static Ataxia”, and it is unique to the dog. For this reason, dogs are very sensitive to cannabis products that contain THC, and pet guardians need to be very careful about giving THC to their dogs, so as to not create this adverse neurologic reaction.
There have been two deaths recorded in Colorado from the use of “edibles”, which are treats containing THC that can be purchased at dispensaries or cooked up in your kitchen. These two fatalities also involved very large amounts of chocolate in the brownies and cookies, and chocolate is much more toxic than THC to dogs. When used together, they create a co-toxicity than can be fatal with high doses of both.
Very low THC cannabis, also known as “hemp” does not contain enough THC to create these adverse reactions. They are a better bet for pets, due to their increased safety. Some experts believe that THC is important to give along with CBD to address certain difficult to treat conditions such as cancer. With further research we will learn more about whether this is true. Hemp-based CBD extracts have been anecdotally reported to help dogs with epilepsy. For treating cancer, it is still unknown whether CBDs can work effectively as a single therapy without THC or other anti-cancer drugs. The research to
objectively determine this is pending. Certainly the use of CBDs for the side-effects of cancer therapies and the improvement of quality of life in these patients has more evidence to support those applications.
Effective Dosages for THC and CBD in Pets
Scientists have not worked out effective dosages for the wide range of clinical applications that have been suggested for cannabis products. Many pet guardians, though, have given their pets cannabis products and have reported success. Some pet owners say the cannabis products didn’t work for them. When the dosages that have been reported to be used by pet parents with existing commercially-available products are compared to dosages published in the scientific literature, the effective dosages
used by these pet parents were much lower.
Dosing by THC Content
My suggestion for dosing, if the product contains THC and you know the concentration, is to start with a dose of 0.1-0.25 mg/kg THC orally, once to twice daily. This dose should allow you to avoid the consequences of static ataxia from the THC. Be warned though, the occasional pet may have what we call an idiosyncratic reaction to that low dose of THC, and still develop Static Ataxia. Once your dog has had about 5 administrations of this small amount over 1-2 weeks, it should develop some degree of
tolerance to the adverse neurologic effects of the THC, and you should be able to increase the dosage gradually to gain the clinical effect you are looking for.
Bron: http://hawthornevet.com/wp-content/uplo ... ur-Pet.pdf
Interview met Rober Silver:
Robert is dus niet tegen het gebruik van THC. Bij ernstige pijn en kanker kan het zeker gebruikt worden.