Fenbendazole is geen natuurlijk middel en deze stof zit in veel ontwormingsmiddelen (ook bij wormen bij varkens, vogels, etc):
Fenbendazole is a benzimidazole anthelmintic, that has broad spectrum, and a wide safety margin.
It binds to 3-tubulin astructural protein that blocks polymerization of tubulin into microtubules, which damages the integrity and the transport function of cells in parasites. The reason behind the wide safety margin is due to its infinity to the parasitic tubules rather than mamilian.
The drug is minimally absorbed after it is given orally. It is metabolized to the active compound oxfendazole sulfoxide and sulfone.
Fenbendazole is excreted in the feces and urine.
Indications:
For use in the removal of ascarids, hookworms, tapeworms, pinworms and roundworms.
Drug Interactions or Contraindications:
Fenbendazole is not recommended to be given concurrently with bromsalan flukicides due to the possiblity that it can cause abortions in animals.
Adverse Reactions:
May cause hypersensitivity.
